Antimicrobial Activity of Azamacrocyclic Complexes of Cu (II), Ni (II), Zn (II) and Ag (I) with their Spectroscopic Approach

Microbial infections are now a day’s more common than during the first half of the century. Although, a number of different classes of antibacterial and antifungal agents have been discovered during last two decades the use is limited due to development of microbial resistance. This situation highlights the need for development of novel, potent, and safe antimicrobial agents. Hence the synthesized aza-macrocyclic metal complexes by in situ one pot template condensation reactions were further confirmed by thermal analysis, UV–vis spectroscopy and molar conductivity measurements. The antimicrobial activity of the complexes has been screened in vitro against bacteria and fungi to access their inhibiting potential. The bioassays indicated that most of the synthesized metal complexes showed potential antibacterial and anti-fungal activity.